Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) Peptide
Quick Overview for Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) Peptide (ABIN983369)
Target
Origin
Source
Application
-
-
Protein Region
- C-Term
-
Sequence
- SLVRTRSRRL TFRKNISKAS RSSEKSLALL KTVIIVLSVF IACWAPLFIL
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-S1PR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
-
Background
-
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.
Alias Symbols: CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, FLJ58121, S1P1
Protein Size: 382 -
Molecular Weight
- 43 kDa
-
Gene ID
- 1901
-
NCBI Accession
- NM_001400, NP_001391
-
UniProt
- P21453
Target
-